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Literature summary for 2.7.1.136 extracted from
- Structure of a phosphorylated derivative of oleandomycin, obtained by reaction of oleandomycin with an extract of an erythromycin-resistant strain of Escherichia coli (1988), J. Antibiot., 41, 823-827.
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | essential | Escherichia coli |  |
| additional information | potassium chloride enhances reactivity, it is added in the reaction mixture at 0.06 M | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | Q47396 | macrolide 2'-phosphotransferase type I, high levels of activity with 14-member ring macrolides and extremely low levels with 16-member ring macrolides, accession code corresponds to nucleotide sequence for several proteins | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + erythromycin | - |
Escherichia coli | ADP + erythromycin-2'-O-phosphate | - |
? | |
| ATP + oleandomycin | - |
Escherichia coli | ADP + oleandomycin 2'-O-phosphate | - |
? | |
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