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Literature summary for 2.7.1.127 extracted from

  • Nalaskowski, M.M.; Windhorst, S.; Stockebrand, M.C.; Mayr, G.W.
    Subcellular localisation of human inositol 1,4,5-trisphosphate 3-kinase C: species-specific use of alternative export sites for nucleo-cytoplasmic shuttling indicates divergent roles of the catalytic and N-terminal domains (2006), Biol. Chem., 387, 583-593.
    View publication on PubMed
Search for more literature for 2.7.1.127

Cloned(Commentary)

Cloned (Comment) Organism
fusion protein of HsIP3K-C with an N-terminal EGFP tag (EGFP/HsIP3KC) is transiently expressed in NRK52E cells Homo sapiens
fusion protein of HsIP3K-C with an N-terminal EGFP tag (EGFP/HsIP3KC) is transiently expressed in NRK52E cells Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Homo sapiens 5737
-
cytoplasm IP3K-C shuttles actively between the nucleus and cytoplasm Rattus norvegicus 5737
-
nucleus enrichment of IP3K-C in the nucleus after leptomycin B treatment. A nuclear export signal has evolved in the catalytic domain as a substitute for an earlier evolved corresponding N-terminal signal (IP3K-B and IP3K-C) Homo sapiens 5634
-
nucleus IP3K-C shuttles actively between the nucleus and cytoplasm. The nuclear import and export activities of rat IP3K-C are both located in its N-terminal domain Rattus norvegicus 5634
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
MeVo cell
-
 Homo sapiens
-
NCI-H1299 cell
-
 Homo sapiens
-
NRK-52E cell
-
 Rattus norvegicus
-
T-47D cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
inositol 1,4,5-trisphosphate 3-kinase C
-
 Homo sapiens
inositol 1,4,5-trisphosphate 3-kinase C
-
 Rattus norvegicus
IP3K-C
-
 Homo sapiens
IP3K-C
-
 Rattus norvegicus