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Literature summary for 2.7.1.127 extracted from
- Inhibition of inositol 1,4,5-trisphosphate by heparin: basal and Ca2+/calmodulin-stimulated activity (1989), Biochem. J., 261, 1059.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| heparin | mixed-type inhibition | Bos taurus |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | up to 30fold stimulation by Ca2+/calmodulin | Bos taurus | |
| Ca2+ | activation by Ca2+/calmodulin | Bos taurus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 1D-myo-inositol 1,4,5-trisphosphate | - |
Bos taurus | ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Bos taurus | |
| Calmodulin | activation by Ca2+/calmodulin | Bos taurus | |
| Calmodulin | up to 30fold stimulation by Ca2+/calmodulin | Bos taurus | |
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