Inhibitors | Comment | Organism | Structure |
---|---|---|---|
hygromycin B | above 0.01 mM, substrate inhibition | Streptomyces hygroscopicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Streptomyces hygroscopicus | |
0.0015 | - |
hygromycin B | pH 7.5, 30°C | Streptomyces hygroscopicus | |
0.076 | - |
ATP | pH 7.5, 30°C | Streptomyces hygroscopicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Streptomyces hygroscopicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
42000 | - |
gel filtration | Streptomyces hygroscopicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + hygromycin B | Streptomyces hygroscopicus | resistance to hygromycin B also occurs in Escherichia coli, where a plasmid encodes a hygromycin B phosphotransferase activity that produces 4-phosphoryl-hygromycin B | ADP + 7''-O-phosphohygromycin B | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces hygroscopicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Streptomyces hygroscopicus |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0003 | - |
- |
Streptomyces hygroscopicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + hygromycin B | - |
Streptomyces hygroscopicus | ADP + 7''-O-phosphohygromycin B | - |
? | |
ATP + hygromycin B | resistance to hygromycin B also occurs in Escherichia coli, where a plasmid encodes a hygromycin B phosphotransferase activity that produces 4-phosphoryl-hygromycin B | Streptomyces hygroscopicus | ADP + 7''-O-phosphohygromycin B | - |
? |