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Literature summary for 2.7.1.113 extracted from

  • Fyrberg, A.; Albertioni, F.; Lotfi, K.
    RNAi depletion of deoxycytidine and deoxyguanosine kinase in human leukemic CEM cells (2008), Nucleosides Nucleotides Nucleic Acids, 27, 712-719.
    View publication on PubMed
Search for more literature for 2.7.1.113

Inhibitors

Inhibitors Comment Organism Structure
2-fluoro-9-beta-D-arabinofuranosyladenine
-
 Homo sapiens
9-beta-D-arabinofuranosylguanine
-
 Homo sapiens
cladribine
-
 Homo sapiens
clofarabine
-
 Homo sapiens
cytarabine
-
 Homo sapiens
gemcitabine
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
CEM cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
DGK
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction dGK depletion in cells results in lower sensitivity to 2-fluoro-9-beta-D-arabinofuranosyladenine, gemcitabine, clofarabine, and 9-beta-D-arabinofuranosylguanine, but slightly higher sensitivity to cladribine and cytarabine Homo sapiens