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Literature summary for 2.7.1.113 extracted from

  • Piskur, J.; Sandrini, M.P.B.; Knecht, W.; Munch-Petersen, B.
    Animal deoxyribonucleoside kinases: 'forward' and 'retrograde' evolution of their substrate specificity (2004), FEBS Lett., 560, 3-6.
    View publication on PubMed
Search for more literature for 2.7.1.113

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Homo sapiens 5739
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 2'-deoxyadenosine Homo sapiens
-
 ADP + 2'-deoxyadenosine 5'-phosphate
-
 ?
ATP + 2'-deoxyguanosine Homo sapiens
-
 ADP + 2'-deoxyguanosine 5'-phosphate
-
 ?
ATP + 2'-deoxyinosine Homo sapiens
-
 ADP + 2'-deoxyinosine 5'-phosphate
-
 ?
additional information Homo sapiens the earliest nucleotide kinase in evolution, probably encoded by the so-called dCK/dGK/TK2-like gene, is the progenitor gene, several duplications of it are the reason for evolutionary occurring of nucleoside kinases with strict substrate specificities in other organism, phylogenetic tree, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q16854
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 2'-deoxyadenosine
-
 Homo sapiens ADP + 2'-deoxyadenosine 5'-phosphate
-
 ?
ATP + 2'-deoxyguanosine
-
 Homo sapiens ADP + 2'-deoxyguanosine 5'-phosphate
-
 ?
ATP + 2'-deoxyinosine
-
 Homo sapiens ADP + 2'-deoxyinosine 5'-phosphate
-
 ?
additional information the earliest nucleotide kinase in evolution, probably encoded by the so-called dCK/dGK/TK2-like gene, is the progenitor gene, several duplications of it are the reason for evolutionary occurring of nucleoside kinases with strict substrate specificities in other organism, phylogenetic tree, overview Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
DGK
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens