Cloned (Comment) | Organism |
---|---|
expression of His-tagged deoxyguanosine kinase in Escherichia coli | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | deoxyguanosine kinase 2 | Mus musculus | 5829 | - |
mitochondrion | - |
Mus musculus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q9QX60 | mitochondrial deoxyguanosine kinase 1 | - |
Mus musculus | Q9QX60 | cytosolic deoxyguanosine kinase 2, amino-terminally truncated isoform | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | low expression levels | Mus musculus | - |
liver | low expression | Mus musculus | - |
spleen | high expression levels | Mus musculus | - |
thymus | high expression | Mus musculus | - |
thymus | high expression levels | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 2',2'-difluorodeoxyguanosine | recombinant mitochondrial deoxyguanosine kinase, 147% of activity with deoxyguanosine | Mus musculus | ADP + 2',2'-difluorodeoxyguanosine 5'-monophosphate | - |
? | |
ATP + 2-chloro-2'-deoxyadenosine | recombinant mitochondrial deoxyguanosine kinase, 200% of activity with deoxyguanosine at 0.005 mM | Mus musculus | ADP + 2-chloro-2'-deoxyadenosine monophosphate | - |
? | |
ATP + deoxyadenosine | recombinant mitochondrial deoxyguanosine kinase, very low activity | Mus musculus | ADP + dAMP | - |
? | |
ATP + deoxyguanosine | - |
Mus musculus | ADP + dGMP | - |
? | |
ATP + deoxyinosine | 10% of activity with deoxyguanosine | Mus musculus | ADP + dIMP | - |
? |