KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.01 | - |
fructose 6-phosphate | 12 h after isoproterenol administration | Rattus norvegicus | |
0.06 | - |
ATP | PFK-1 | Rattus norvegicus | |
0.086 | - |
D-fructose 6-phosphate | - |
Rattus norvegicus | |
0.1 | - |
ATP | 12 h after isoproterenol administration, PFK-1 | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | 4.2 mol phosphate/mol of enzyme in rats treated with 3 doses of isoproterenol, 3 mol phosphate/mol enzyme after dephosphorylation, presence of phosphate groups influences the kinetic properties of PFK-1 | Rattus norvegicus |
Purification (Comment) | Organism |
---|---|
DEAE Sepharose, Affi-gel blue | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
submandibular gland | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
slight increase in rats 12 h after isoproterenol administration | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-fructose 6-phosphate | - |
Rattus norvegicus | ADP + D-fructose 1,6-bisphosphate | - |
? |