Protein Variants | Comment | Organism |
---|---|---|
F76A | 62fold increase in Km for ATP | Escherichia coli |
F76W | apparant Kms for ATP, ITP, GTP, CTP and UTP | Escherichia coli |
F76Y | apparant Kms for ATP, ITP, GTP, CTP and UTP | Escherichia coli |
R111E | apparant Kms for ATP, ITP, GTP, CTP and UTP | Escherichia coli |
R11A | apparant Kms for ATP, ITP, GTP, CTP and UTP | Escherichia coli |
R77A | apparant Kms for ATP, ITP, GTP, CTP and UTP | Escherichia coli |
R77D | apparant Kms for ATP, ITP, GTP, CTP and UTP | Escherichia coli |
R77E | apparant Kms for ATP, ITP, GTP, CTP and UTP | Escherichia coli |
R77L | apparant Kms for ATP, ITP, GTP, CTP and UTP | Escherichia coli |
R82A | 20fold increase in Km for ATP | Escherichia coli |
R82E | apparant Kms for ATP, ITP, GTP, CTP and UTP | Escherichia coli |
Y41A | 49fold increase in Km for ATP | Escherichia coli |
Y41F | apparant Kms for ATP, ITP, GTP, CTP and UTP | Escherichia coli |
Y41L | apparant Kms for ATP, ITP, GTP, CTP and UTP | Escherichia coli |
Y41W | apparant Kms for ATP, ITP, GTP, CTP and UTP | Escherichia coli |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.21 | - |
ATP | pH 7.2, 30°C | Escherichia coli | |
2.2 | - |
ITP | pH 7.2, 30°C | Escherichia coli | |
4.3 | - |
GTP | pH 7.2, 30°C | Escherichia coli | |
5.1 | - |
UTP | pH 7.2, 30°C | Escherichia coli | |
11 | - |
CTP | pH 7.2, 30°C | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P0A796 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + D-fructose 6-phosphate | - |
Escherichia coli | CDP + D-fructose 1,6-bisphosphate | - |
? | |
GTP + D-fructose 6-phosphate | - |
Escherichia coli | GDP + D-fructose 1,6-bisphosphate | - |
? | |
ITP + D-fructose 6-phosphate | - |
Escherichia coli | IDP + D-fructose 1,6-bisphosphate | - |
? | |
UTP + D-fructose 6-phosphate | - |
Escherichia coli | UDP + D-fructose 1,6-bisphosphate | - |
? |