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Literature summary for 2.7.1.11 extracted from

  • Krause, U.; Wegener, G.
    6-Phosphofructokinase from frog skeletal muscle: purification and properties (1990), Biochem. Soc. Trans., 18, 592-593.
    View publication on PubMed
Search for more literature for 2.7.1.11

Activating Compound

Activating Compound Comment Organism Structure
D-fructose 1,6-bisphosphate half-maximal activation at 0.0035 mM Rana temporaria
D-fructose 2,6-bisphosphate activation Rana temporaria
D-Glucose 1,6-bisphosphate half-maximal activation at 0.013 mM Rana temporaria

Inhibitors

Inhibitors Comment Organism Structure
ATP 7.5 mM, 98% inhibition; fructose 2,6-bisphosphate partially reverses inhibition Rana temporaria
citrate with glucose 1,6-bisphosphate or fructose 1,6-bisphosphate as activator Rana temporaria
MgATP2-
-
 Rana temporaria

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required for activity Rana temporaria
Mg2+ MgATP is the active substrate Rana temporaria

Organism

Organism UniProt Comment Textmining
Rana temporaria
-
 frog
-

Purification (Commentary)

Purification (Comment) Organism
partial Rana temporaria

Source Tissue

Source Tissue Comment Organism Textmining
muscle
-
 Rana temporaria
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
80
-
-
 Rana temporaria

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-fructose 6-phosphate
-
 Rana temporaria ADP + D-fructose 1,6-bisphosphate
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at Rana temporaria