Activating Compound | Comment | Organism | Structure |
---|---|---|---|
dithiothreitol | slight stimulation of activity | Rattus norvegicus | |
Triton X-100 | - |
Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CDP | - |
Rattus norvegicus | |
EDTA | - |
Rattus norvegicus | |
additional information | product of the reaction, dolichyl phosphate, is noninhibitory, no inhibition by dithiothreitol | Rattus norvegicus | |
Triton X-100 | above 0.5% w/v, activation below | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.05 | - |
dolichol | pH 7.4, 37°C | Rattus norvegicus | |
4 | - |
CTP | pH 7.4, 37°C | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Rattus norvegicus | |
Mg2+ | - |
Rattus norvegicus | |
Mn2+ | - |
Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + dolichol | Rattus norvegicus | - |
CDP + dolichyl phosphate | - |
? | |
CTP + dolichol | Rattus norvegicus Wistar | - |
CDP + dolichyl phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
rat | - |
Rattus norvegicus | - |
Wistar | - |
Rattus norvegicus Wistar | - |
Wistar | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + dolichol | - |
Rattus norvegicus | CDP + dolichyl phosphate | - |
? | |
CTP + dolichol | - |
Rattus norvegicus Wistar | CDP + dolichyl phosphate | - |
? | |
additional information | ATP cannot replace CTP | Rattus norvegicus | ? | - |
? | |
additional information | ATP cannot replace CTP | Rattus norvegicus Wistar | ? | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | 7.5 | - |
Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
4 | 10 | about half-maximal activity at pH 6.0 and 8.0 | Rattus norvegicus |