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Literature summary for 2.7.1.107 extracted from
- Is there a role for diacylglycerol kinase-zeta in cell cycle regulation? (2008), Adv. Enzyme Regul., 48, 31-39.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | DGKzeta interacts with and is regulated by the retinoblastoma protein | Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in HEK-293, U2OS, MCF-7, Swiss3-T3, MEF, and Phoenix cells | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 1,2-diacylglycerol | Homo sapiens | - |
ADP + 1,2-diacyl-sn-glycerol 3-phosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q13574 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 1,2-diacylglycerol | - |
Homo sapiens | ADP + 1,2-diacyl-sn-glycerol 3-phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DGKzeta | - |
Homo sapiens |
| diacylglycerol kinase-zeta | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Homo sapiens | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | neither overexpression of wild type nor kinase-inactive DGKzeta affects cell cycle distribution | Homo sapiens |
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