Literature summary for 2.7.1.107 extracted from

Merino, E.; Sanjuan, M.A.; Moraga, I.; Cipres, A.; Merida, I.
Role of the diacylglycerol kinase alpha-conserved domains in membrane targeting in intact T cells (2007), J. Biol. Chem., 282, 35396-35404.

Search for more literature for 2.7.1.107

Cloned(Commentary)

Cloned (Comment)	Organism
expression in T lymphocyte and COS-7 cells	Mus musculus

Protein Variants

Protein Variants	Comment	Organism
additional information	construction of mutant protein lacking the regulatory N-terminus and both C1 domains. Mutant is enzymatically active. deletion analysis reveals that the C1 domains are essential for plasma membrane targeting in intact cells but unnecessary for catalytic activity. The C-terminal sequence is required for membrane-binding in a phosphatidic acid-dependent manner. In the absence of the calcium binding domain, receptor-dependent translocation of the truncated protein is regulated by phosphorylation of residue Y335	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	O88673	diacylglycerol kinase alpha	-

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Release 2023.1 (January 2023)