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Literature summary for 2.7.1.107 extracted from

  • Clarke, C.J.; Ohanian, V.; Ohanian, J.
    Norepinephrine and endothelin activate diacylglycerol kinases in caveolae/rafts of rat mesenteric arteries: agonist-specific role of PI3-kinase (2007), Am. J. Physiol. Heart Circ. Physiol., 292, H2248-H2256.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
endothelin-1 activates diacylglycerol kinase in caveolae/rafts and noncaveolae/rafts of mesenteric arteries. Activation does not depend on phosphatidylinositol 3-kinase. In response to norepinephrin, but not to epithelin-1, protein kinase PKB translocates to caveolae/rafts Rattus norvegicus
norepinephrine stimulates an increase in diacylglycerol kinase activity in caveolae/rafts of mesenteric arteries. Activation depends on phosphatidylinositol 3-kinase. In response to norepinephrin, but not to epithelin-1, protein kinase PKB translocates to caveolae/rafts Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
mesenteric artery
-
Rattus norvegicus
-