Any feedback?
Literature summary for 2.7.1.106 extracted from
- Regulation of glucose 1,6-bisphosphate level in liver. III. Purification and properties of bovine glucose 1,6-bisphosphate synthase (1978), J. Biochem., 83, 1721-1730.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| D-fructose 1,6-diphosphate | strong, liver | Bos taurus |  |
| glycerate 2,3-diphosphate | strong, liver | Bos taurus | |
| phosphoenolpyruvate | strong | Bos taurus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00023 | - |
3-phospho-D-glyceroyl 1-phosphate | 25°C, pH 7.5, liver enzyme peak I | Bos taurus | |
| 0.00028 | - |
3-phospho-D-glyceroyl 1-phosphate | 25°C, pH 7.5, liver enzyme peak II | Bos taurus | |
| 0.00045 | - |
3-phospho-D-glyceroyl 1-phosphate | 25°C, pH 7.5, erythrocyte enzyme | Bos taurus | |
| 0.009 | - |
D-glucose 1-phosphate | 25°C, pH 7.5, liver enzyme peak I | Bos taurus | |
| 0.015 | - |
D-glucose 6-phosphate | 25°C, pH 7.5, liver enzyme peak I | Bos taurus | |
| 0.059 | - |
D-glucose 1-phosphate | 25°C, pH 7.5, liver enzyme peak II | Bos taurus | |
| 0.061 | - |
D-glucose 6-phosphate | 25°C, pH 7.5, liver enzyme peak II | Bos taurus | |
| 0.16 | - |
D-glucose 1-phosphate | 25°C, pH 7.5, erythrocyte enzyme | Bos taurus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| soluble | - |
Bos taurus | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Bos taurus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-phospho-D-glyceroyl phosphate + D-glucose 1-phosphate | Bos taurus | - |
3-phospho-D-glycerate + D-glucose 1,6-bisphosphate | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| liver: 2 isozymes | Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | - |
Bos taurus | - |
| liver | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.0045 | - |
liver enzyme | Bos taurus |
| 0.136 | - |
erythrocyte enzyme | Bos taurus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-phospho-D-glyceroyl phosphate + D-glucose 1-phosphate | - |
Bos taurus | 3-phospho-D-glycerate + D-glucose 1,6-bisphosphate | - |
r | |
| 3-phospho-D-glyceroyl phosphate + D-glucose 1-phosphate | i.e. 1,3-diphosphoglycerate | Bos taurus | 3-phospho-D-glycerate + D-glucose 1,6-bisphosphate | - |
r | |
| 3-phospho-D-glyceroyl phosphate + D-glucose 1-phosphate | specific for 3-phospho-D-glyceroyl phosphate | Bos taurus | 3-phospho-D-glycerate + D-glucose 1,6-bisphosphate | - |
r | |
| 3-phospho-D-glyceroyl phosphate + D-glucose 1-phosphate | no acceptor activity mannose 6-phosphate | Bos taurus | 3-phospho-D-glycerate + D-glucose 1,6-bisphosphate | - |
r | |
| 3-phospho-D-glyceroyl phosphate + D-glucose 6-phosphate | - |
Bos taurus | 3-phospho-D-glycerate + D-glucose 1,6-bisphosphate | - |
? | |
| 3-phospho-D-glyceroyl phosphate + D-mannose 1-phosphate | - |
Bos taurus | 3-phospho-D-glycerate + D-mannose 1,6-bisphosphate | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at | Bos taurus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
