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Literature summary for 2.7.1.1 extracted from

  • Vilches-Flores, A.; Tovar, A.R.; Marin-Hernandez, A.; Rojas-Ochoa, A.; Fernandez-Mejia, C.
    Biotin increases glucokinase expression via soluble guanylate cyclase/protein kinase G, adenosine triphosphate production and autocrine action of insulin in pancreatic rat islets (2009), J. Nutr. Biochem., 21, 606-612.
    View publication on PubMed
Search for more literature for 2.7.1.1

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreatic islet
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-glucose
-
 Rattus norvegicus ADP + D-glucose 6-phosphate
-
 ?

Synonyms

Synonyms Comment Organism
glucokinase
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus biotin increases glucokinase expression, inhibition of soluble guanylate cyclase or protein kinase G signalling suppresses biotin-induced glucokinase expression, inhibition of insulin secretion with diazoxide or nifedipine prevents biotin-stimulated glucokinase mRNA increase up