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Literature summary for 2.7.1.1 extracted from

  • Roncero, I.; Sanz, C.; Alvarez, E.; Vazquez, P.; Barrio, P.A.; Blazquez, E.
    Glucokinase and glucokinase regulatory proteins are functionally coexpressed before birth in the rat brain (2009), J. Neuroendocrinol., 21, 973-981.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
glucokinase regulatory protein
-
Rattus norvegicus
additional information no product inhibition by D-glucose 6-phosphate Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
52000
-
SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain the presence of glucokinase phosphorylating activity is detected in different brain areas of 21-day-old foetuses with a contribution to the total glucose-phosphorylating activity of between 17.2% and 12.4% Rattus norvegicus
-
brain stem the contribution of glucokinase to total glucose-phosphorylating activity is of 12.4% in the brainstem Rattus norvegicus
-
cerebellum the contribution of glucokinase to total glucose-phosphorylating activity is of 13.3% in the cerebellum Rattus norvegicus
-
cerebral cortex the contribution of glucokinase to total glucose-phosphorylating activity is of 15.3% in the cerebral cortex Rattus norvegicus
-
hypothalamus the hypothalamus is the region of maximum activity (17.2%) Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-glucose
-
Rattus norvegicus ADP + D-glucose 6-phosphate
-
?

Synonyms

Synonyms Comment Organism
glucokinase
-
Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
ATP
-
Rattus norvegicus