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Literature summary for 2.7.1.1 extracted from

  • Cifuentes, D.; Martinez-Pons, C.; Garcia-Rocha, M.; Galina, A.; Ribas de Pouplana, L.; Guinovart, J.J.
    Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver (2008), J. Biol. Chem., 283, 5642-5649.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in FTO-2B cells Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
D-glucose 6-phosphate D-glucose 6-phosphate at physiological concentrations is a potent inhibitor of hexokinase isoforms I and II but not of hexokinase type IV Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion hexokinase type I Rattus norvegicus 5739
-
soluble glucokinase Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatoma cell
-
Rattus norvegicus
-
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-glucose
-
Rattus norvegicus ADP + D-glucose 6-phosphate
-
?

Synonyms

Synonyms Comment Organism
ATP:D-hexose 6-phosphotransferase
-
Rattus norvegicus
glucokinase
-
Rattus norvegicus
hexokinase type I substitutes for glucokinase in hepatomas and in embryonic livers Rattus norvegicus
hexokinase type II substitutes for glucokinase in hepatomas and in embryonic livers Rattus norvegicus
hexokinase type IV
-
Rattus norvegicus
HKI substitutes for glucokinase in hepatomas and in embryonic livers Rattus norvegicus
HKII substitutes for glucokinase in hepatomas and in embryonic livers Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
ATP
-
Rattus norvegicus