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Literature summary for 2.7.1.1 extracted from
- Inhibition of red cell and yeast hexokinase by triethyltin bromide [(C2H5)3SnBr] (1980), Biochem. Biophys. Res. Commun., 95, 758-764.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Triethyltin bromide | 0.5 mM, 1 h, 37°C, nearly complete inhibition; selective inhibitor, sugar substrates D-glucose and D-mannose protect | Homo sapiens |  |
| Triethyltin bromide | selective inhibitor, sugar substrates D-glucose and D-mannose protect | Saccharomyces cerevisiae | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-glucose + ATP | Homo sapiens | glycolytic enzyme | D-glucose 6-phosphate + ADP | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Saccharomyces cerevisiae | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-glucose + ATP | - |
Homo sapiens | ADP + D-glucose 6-phosphate | - |
? | |
| D-glucose + ATP | - |
Saccharomyces cerevisiae | ADP + D-glucose 6-phosphate | - |
? | |
| D-glucose + ATP | glycolytic enzyme | Homo sapiens | D-glucose 6-phosphate + ADP | - |
? | |
| D-mannose + ATP | - |
Homo sapiens | ADP + D-mannose 6-phosphate | - |
? | |
| D-mannose + ATP | - |
Saccharomyces cerevisiae | ADP + D-mannose 6-phosphate | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Homo sapiens | |
| ATP | - |
Saccharomyces cerevisiae | |
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