Any feedback?
Literature summary for 2.6.1.9 extracted from
- Imidazolylacetolphosphate:L-glutamate aminotransferase. Purification and physical properties (1967), J. Biol. Chem., 242, 1168-1174.
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 59000 | - |
equilibrium centrifugation, pyridoxal phosphate analysis, spectrophotometric assay, phosphate analysis, viscometry | Salmonella enterica subsp. enterica serovar Typhimurium |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate | Salmonella enterica subsp. enterica serovar Typhimurium | eighth step in histidine biosynthesis | L-histidinol phosphate + 2-oxoglutarate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Salmonella enterica subsp. enterica serovar Typhimurium | - |
derepressed histidine auxotroph | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| from derepressed histidine auxotrophs, 95% pure | Salmonella enterica subsp. enterica serovar Typhimurium |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 1885 | - |
- |
Salmonella enterica subsp. enterica serovar Typhimurium |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate | eighth step in histidine biosynthesis | Salmonella enterica subsp. enterica serovar Typhimurium | L-histidinol phosphate + 2-oxoglutarate | - |
? | |
| L-histidinol phosphate + 2-oxoglutarate | - |
Salmonella enterica subsp. enterica serovar Typhimurium | 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-Glu | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | marked tendency to polymerize upon ageing | Salmonella enterica subsp. enterica serovar Typhimurium |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Salmonella enterica subsp. enterica serovar Typhimurium |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 6 | - |
unstable below | Salmonella enterica subsp. enterica serovar Typhimurium |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | a pyridoxal phosphate protein | Salmonella enterica subsp. enterica serovar Typhimurium | |
| pyridoxal 5'-phosphate | 1 pyridoxal phosphate group associated with each molecule of enzyme | Salmonella enterica subsp. enterica serovar Typhimurium | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
