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Literature summary for 2.6.1.7 extracted from

  • Knyihar-Csillik, E.; Chadaide, Z.; Mihaly, A.; Krisztin-Peva, B.; Fenyo, R.; Vecsei, L.
    Effect of 6-hydroxydopamine treatment on kynurenine aminotransferase-I (KAT-I) immunoreactivity of neurons and glial cells in the rat substantia nigra (2006), Acta Neuropathol., 112, 127-137.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Rattus norvegicus Q08415
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Source Tissue

Source Tissue Comment Organism Textmining
astrocyte astrocytes in the substantia nigra express KAT-I under normal conditions. The amount of this enzyme increases after administration of 6-hydroxydopamine Rattus norvegicus
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glial cell microglial cells become KAT-I immunoreactive only after treatment with 6-hydroxydopamine Rattus norvegicus
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neuron
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Rattus norvegicus
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substantia nigra pars compacta. Neurons and glial cells. Treatment with 6-hydroxydopamine produces loss of the majority of nigral neurons. KAT-I diminished considerably in the remaining neurons. Astrocytes in the substantia nigra express KAT-I under normal conditions, the amount of this enzyme increases after administration of 6-hydroxydopamine. Microglial cells become KAT-I immunoreactive only after treatment with 6-hydroxydopamine Rattus norvegicus
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Synonyms

Synonyms Comment Organism
KAT-I
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Rattus norvegicus
kynurenine aminotransferase-I
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Rattus norvegicus