Crystallization (Comment) | Organism |
---|---|
to 2.15 A resolution. The active site is in a closed conformation, and pyridoxal 5'-phosphate forms an internal aldimine linkage to Lys 202. Residue Val 340 near the active site might be responsible in closing the active site | Trichomonas vaginalis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Iodide | - |
Trichomonas vaginalis | |
additional information | not inhibitory: chloride, fluoride and bromide up to 200 mM | Trichomonas vaginalis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0544 | - |
O-phospho-L-serine | pH 8.5, 22°C | Trichomonas vaginalis | |
0.2028 | - |
2-oxoglutarate | pH 8.5, 22°C | Trichomonas vaginalis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trichomonas vaginalis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
O-phospho-L-serine + 2-oxoglutarate | - |
Trichomonas vaginalis | 3-phosphonooxypyruvate + L-glutamate | - |
r |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
200 | - |
pH 8.5, 22°C | Trichomonas vaginalis | Iodide |