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Literature summary for 2.6.1.51 extracted from

  • Sallach, H.J.
    Formation of serine from hydroxypyruvate and L-alanine (1956), J. Biol. Chem., 223, 1101-1108.
    View publication on PubMed
Search for more literature for 2.6.1.51

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-alanine + 3-hydroxypyruvate Canis lupus familiaris
-
 pyruvate + L-serine
-
 r
L-serine + pyruvate Canis lupus familiaris
-
 3-hydroxypyruvate + L-alanine
-
 r

Organism

Organism UniProt Comment Textmining
Canis lupus familiaris
-
 dog
-
Neurospora crassa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Canis lupus familiaris
-
liver
-
 Canis lupus familiaris
-

Storage Stability

Storage Stability Organism
5°C, acetone powder of fresh liver stored in a vacuum desiccator over aluminia retains its enzymatic activity for months Canis lupus familiaris

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutamic acid + 3-hydroxypyruvate
-
 Canis lupus familiaris 2-oxo-1,5-pentandioate + serine
-
 r
glycine + 3-hydroxypyruvate
-
 Canis lupus familiaris glyoxylate + L-serine
-
 r
glycine + 3-hydroxypyruvate
-
 Canis lupus familiaris L-serine + glyoxylate
-
 r
L-alanine + 3-hydroxypyruvate
-
 Neurospora crassa pyruvate + L-serine
-
 r
L-alanine + 3-hydroxypyruvate
-
 Canis lupus familiaris pyruvate + L-serine
-
 r
L-serine + pyruvate
-
 Canis lupus familiaris 3-hydroxypyruvate + L-alanine
-
 r
additional information D-alanine is no substrate Canis lupus familiaris ?
-
 ?

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Canis lupus familiaris