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Literature summary for 2.6.1.5 extracted from
- Role of glucocorticoids and resident liver macrophages in induction of tyrosine aminotransferase (2008), Biochemistry, 73, 305-309.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Dextran sulfate | dextran sulfate inhibits TAT activity but conditioned macrophage medium reliably increases enzyme activity in hepatocytes | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hepatocyte | - |
Rattus norvegicus | - |
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tyrosine + 2-oxoglutarate | - |
Rattus norvegicus | 4-hydroxyphenylpyruvate + L-glutamate | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TAT | - |
Rattus norvegicus |
| tyrosine aminotransferase | - |
Rattus norvegicus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Rattus norvegicus | in a combined culture of hepatocytes and non-parenchymal liver cells, reproducing intercellular interactions in vitro, cortisol and non-parenchymal cells exhibit an additive effect on TAT activity | up |
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Release 2023.1 (January 2023)
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