Literature summary for 2.6.1.48 extracted from

Park, S.J.; Kim, E.Y.; Noh, W.; Park, H.M.; Oh, Y.H.; Lee, S.H.; Song, B.K.; Jegal, J.; Lee, S.Y.
Metabolic engineering of Escherichia coli for the production of 5-aminovalerate and glutarate as C5 platform chemicals (2013), Metab. Eng., 16, 42-47.

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Application

Application	Comment	Organism
synthesis	expression of the Pseudomonas putida davAB genes encoding delta-aminovaleramidase and lysine 2-monooxygenase, respectively, in Escherichia coli. When the davAB genes are introduced into recombinant E. coli strain XQ56 allowing enhanced L-lysine synthesis, 0.27 and 0.5g/l of 5-aminovalerate are produced directly from glucose by batch- and fed-batch cultures, respectively. Further conversion of 5-aminovalerate into glutarate can be achieved by expression of the Pseudomonas putida gabTD genes encoding 5-aminovalerate aminotransferase and glutarate semialdehyde dehydrogenase. In a medium containing 20g/l glucose, 10g/l L-lysine and 10g/l alpha-ketoglutarate, this strain produces 1.7g/l of glutarate	Pseudomonas putida

Organism

Organism	UniProt	Comment	Textmining
Pseudomonas putida	-	-	-
Pseudomonas putida ATCC 12633	-	-	-

Synonyms

Synonyms	Comment	Organism
DavA	-	Pseudomonas putida

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Release 2023.1 (January 2023)