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Literature summary for 2.6.1.44 extracted from
- Role of alanine:glyoxylate aminotransferase 2 in metabolism of asymmetric dimethylarginine in the settings of asymmetric dimethylarginine overload and bilateral nephrectomy (2014), Nephrol. Dial. Transplant., 29, 2035-2042.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | infusion of asymmetric dimethylarginines causes a 3- to 4fold increase in plasma and urine asymmetric dimethylarginine levels and a 2- to 3fold increase in plasma and urine levels of the asymmetric dimethylarginine-specific metabolite of AGXT2, alpha-keto-delTA-(N,N-dimethylguanidino)valeric acid. Plasma levels of alpha-keto-delTA-(N,N-dimethylguanidino)valeric acid are elevated 32fold in the mice, which underwent bilateral nephrectomy. Neither bilateral nephrectomy nor asymmetric dimethylarginine infusion causes upregulation of AGXT2 expression or activity | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AGXT2 | - |
Mus musculus |
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Release 2023.1 (January 2023)
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