Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.6.1.44 extracted from

  • Djordjevic, S.; Zhang, X.; Bartlam, M.; Ye, S.; Rao, Z.; Danpure, C.J.
    Structural implications of a G170R mutation of alanine:glyoxylate aminotransferase that is associated with peroxisome-to-mitochondrion mistargeting (2010), Acta Crystallogr. Sect. F, 66, 233-236.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.6.1.44

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli JM109 cells Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
using 10% (w/v) PEG 4000 in 0.1 M Na HEPES pH 7.5 Homo sapiens

Protein Variants

Protein Variants Comment Organism
G170R the mutant shows decrease in protein stability Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
aminooxyacetic acid
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
peroxisome
-
 Homo sapiens 5777
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-alanine + glyoxylate Homo sapiens
-
 pyruvate + glycine
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P21549
-
-

Purification (Commentary)

Purification (Comment) Organism
nickel-resin affinity chromatography, gel filtration Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-alanine + glyoxylate
-
 Homo sapiens pyruvate + glycine
-
 ?

Synonyms

Synonyms Comment Organism
AGT
-
 Homo sapiens
alanine:glyoxylate aminotransferase
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Homo sapiens