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Literature summary for 2.6.1.44 extracted from

  • Ikeda, M.; Kanouchi, H.; Minatogawa, Y.
    Characterization of peroxisomal targeting signals on alanine: glyoxylate aminotransferase (2008), Biol. Pharm. Bull., 31, 131-134.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in HeLa cell Homo sapiens
expression vectors of the enhanced green fluorescent protein-tagged alanine:glyoxylate aminotransferase and deletion mutants are introduced into HeLa cells to identify the peroxisomal targeting signal of the alanine:glyoxylate aminotransferase Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information expression of green fluorescent protein-tagged enzyme in HeLa cells. Identification of two sites of peroxisomal targeting sequences around amino acids 59-66 and 389-392. A truncated mutant missing the COOH-terminal amino acids, 1—216 is not targeted into peroxisome. Deletion mutant lacking amino acids 221—390 or amino acids 221—389 are not targeted into peroxisome. Deltion mutants lacking 221—388 or 221—386 are targeted Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
peroxisome sequence contains two sites of peroxisomal targeting sequences around amino acids 59-66 and 389-392 Homo sapiens 5777
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Synonyms

Synonyms Comment Organism
AGT
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Homo sapiens
alanine:glyoxylate aminotransferase
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Homo sapiens