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Literature summary for 2.6.1.43 extracted from
- Production of delta-aminolevulinic acid: characterization of murine liver 4,5-dioxovaleric acid: L-alanine aminotransferase (1991), Int. J. Biochem., 23, 803-810.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5-aminolevulinate | - |
Mus musculus |  |
| beta-chloroalanine | - |
Mus musculus | |
| gabaculine | - |
Mus musculus | |
| glyoxylic acid | - |
Mus musculus | |
| hemin | - |
Mus musculus | |
| methylglyoxal | - |
Mus musculus | |
| pyruvate | - |
Mus musculus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.22 | - |
4,5-Dioxopentanoate | - |
Mus musculus | |
| 0.97 | - |
L-alanine | - |
Mus musculus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-alanine + 4,5-dioxopentanoate | Mus musculus | - |
5-aminolevulinate + pyruvate | - |
ir | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
mouse | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hepatocyte | - |
Mus musculus | - |
| liver | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-alanine + 4,5-dioxopentanoate | - |
Mus musculus | 5-aminolevulinate + pyruvate | - |
ir | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 8 | - |
Mus musculus |
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