Literature summary for 2.6.1.2 extracted from

Matthews, C.C.; Zielke, H.R.; Parks, D.A.; Fishman, P.S.
Glutamate-pyruvate transaminase protects against glutamate toxicity in hippocampal slices (2003), Brain Res., 978, 59-64.

Application

Application	Comment	Organism
medicine	enzyme is an effective neuroprotectant against glutamate excitotoxicity. When exposure is limited to endogenously released glutamate, neuroprotection by enzyme is not dependent on added pyruvate	Rattus norvegicus

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	7 days old	-

Source Tissue	Comment	Organism	Textmining
hippocampus	-	Rattus norvegicus	-

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Release 2023.1 (January 2023)