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Literature summary for 2.6.1.19 extracted from
- The effects of GABA agonists on glutamic acid decarboxylase, GABA-transaminase, activin, salmon gonadotrophin-releasing hormone and tyrosine hydroxylase mRNA in the goldfish (Carassius auratus) neuroendocrine brain (2007), J. Neuroendocrinol., 19, 390-396.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Baclofen | injection of 0.01 mg/g body weight reduces GABA-T mRNA level 2fold; i.p. injection of sexually regressed female goldfish results in significant increase in serum luteinising hormone after 6 h. About 2fold decrease both in glutamic acid decarboxylase 67 and gamma-aminobutanoate transaminase mRNa in the hypothalamus | Carassius auratus |  |
| Muscimol | injection of 0.001 mg/g body weight reduces GABA-T mRNA level 15fold; i.p. injection of sexually regressed female goldfish results in significant increase in serum luteinising hormone after 6 h. About 10fold decrease in glutamic acid decarboxylase 65 and 15fold in gamma-aminobutanoate transaminase mRNa in the hypothalamus | Carassius auratus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Carassius auratus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Carassius auratus | - |
| hypothalamus | - |
Carassius auratus | - |
| telencephalon | - |
Carassius auratus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GABA-T | - |
Carassius auratus |
| GABA-transaminase | - |
Carassius auratus |
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