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Literature summary for 2.6.1.19 extracted from

  • Schousboe, A.; Wu, J.Y.; Roberts, E.
    Subunit structure and kinetic properties of 4-aminobutyrate-2-ketoglutarate transaminase purified from mouse brain (1974), J. Neurochem., 23, 1189-1195.
    View publication on PubMed
Search for more literature for 2.6.1.19

Inhibitors

Inhibitors Comment Organism Structure
2-oxoadipic acid
-
 Mus musculus
3-Mercaptopropionic acid
-
 Mus musculus
acetic acid
-
 Mus musculus
adipic acid
-
 Mus musculus
Ba2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
Butyric acid
-
 Mus musculus
Ca2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
Cd2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
Co2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
Cu2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
dioxan 5% v/v Mus musculus
Divalent metal ions with decreasing efficiency: Hg2+, Cd2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
ethanol 10% v/v, weak Mus musculus
glutamic acid
-
 Mus musculus
HgCl2 strong, 50% inhibition at 0.007 mM Mus musculus
hydrazine
-
 Mus musculus
hydroxylamine
-
 Mus musculus
methanol 10% v/v, weak Mus musculus
Mg2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
Mn2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
Ni2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus
p-chloromercuribenzoate strong Mus musculus
pimelic acid
-
 Mus musculus
propionic acid
-
 Mus musculus
SH-group reagents
-
 Mus musculus
Sr2+ order of decreasing inhibitory potency: Hg2+, Cd2+, Cu2+, Co2+, Ba2+, Sr2+, Ni2+, Mn2+, Ca2+, Mg2+ Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
53000
-
 1 * 53000 + 1 * 58000, SDS-PAGE Mus musculus
58000
-
 1 * 53000 + 1 * 58000, SDS-PAGE Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-aminobutanoate + 2-oxoglutarate
-
 Mus musculus 4-oxobutanoate + L-glutamate
-
 r

Subunits

Subunits Comment Organism
dimer 1 * 53000 + 1 * 58000, SDS-PAGE Mus musculus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.013
-
 3-Mercaptopropionic acid
-
 Mus musculus