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Literature summary for 2.6.1.16 extracted from

  • Chmara, H.; Andruszkiewicz, R.; Borowski, E.
    Inactivation of glucosamine-6-phosphate synthetase from Salmonella typhimurium LT 2 SL 1027 by N beta-fumarylcarboxyamido-L-2,3-diamino-propionic acid (1984), Biochem. Biophys. Res. Commun., 120, 865-872.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
N3-fumarylcarboxyamido-L-2,3-diaminopropionic acid competitive with L-glutamine Salmonella enterica subsp. enterica serovar Typhimurium

Organism

Organism UniProt Comment Textmining
Salmonella enterica subsp. enterica serovar Typhimurium
-
LT2
-

Storage Stability

Storage Stability Organism
4°C, 25 mM potassium phosphate buffer, pH 7.5, 1 mM EGTA, 2 mM dithiothreitol, 500 mM sucrose, stable for up to 2 or 3 weeks Salmonella enterica subsp. enterica serovar Typhimurium

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-glutamine + D-fructose 6-phosphate
-
Salmonella enterica subsp. enterica serovar Typhimurium L-glutamate + D-glucosamine 6-phosphate
-
?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.125
-
N3-fumarylcarboxyamido-L-2,3-diaminopropionic acid pH 7.5, 37°C Salmonella enterica subsp. enterica serovar Typhimurium