Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.5.1.87 extracted from

  • Sato, M.; Sato, K.; Nishikawa, S.; Hirata, A.; Kato, J.; Nakano, A.
    The yeast RER2 gene, identified by endoplasmic reticulum protein localization mutations, encodes cis-prenyltransferase, a key enzyme in dolichol synthesis (1999), Mol. Cell. Biol., 19, 471-483.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.5.1.87

Cloned(Commentary)

Cloned (Comment) Organism
-
 Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum peripheral but tightly associated membrane protein, localized to a subregion of the endoplasmic reticulum membrane that is specialized for dolichol synthesis Saccharomyces cerevisiae 5783
-

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae C7GM47
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2E,6E)-farnesyl diphosphate + n isopentenyl diphosphate
-
 Saccharomyces cerevisiae n diphosphate + di-trans,poly-cis-polyprenyl diphosphate
-
 ?

Synonyms

Synonyms Comment Organism
Dedol-PP synthase
-
 Saccharomyces cerevisiae
RER2
-
 Saccharomyces cerevisiae

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Saccharomyces cerevisiae

General Information

General Information Comment Organism
malfunction rer2 mutant is defective in both N- and O-linked glycosylation in the endoplasmic reticulum, the rer2 mutant is deficient in the activity of cis-prenyltransferase, a key enzyme of dolichol synthesis Saccharomyces cerevisiae
physiological function RER2 encodes a key enzyme of dolichol synthesis Saccharomyces cerevisiae