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Literature summary for 2.5.1.85 extracted from

  • Kim, E.H.; Lee, Y.; Kim, H.U.
    Fibrillin 5 is essential for plastoquinone-9 biosynthesis by binding to solanesyl diphosphate synthases in Arabidopsis (2015), Plant Cell, 27, 2956-2971.
    View publication on PubMedView publication on EuropePMC
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Activating Compound

Activating Compound Comment Organism Structure
fibrillin 5B FBN5-B, fibrillin 5B specifically interacts with solanesyl diphosphate synthase 1, which biosynthesize the solanesyl moiety of plastoquinone-9. Plants containing defective FBN5-B accumulate less plastoquinone-9 and its cyclized product, plastochromanol-8, but the levels of tocopherols are not affected. Homozygous mutations in FBN5 are seedling-lethal. FBN5-B is required for PQ-9 biosynthesis through its interaction with enzyme SPS. FBN5 binding to the hydrophobic solanesyl moiety, which is generated by SPS1, in FBN5 B/SPS homodimeric complexes stimulates the enzyme activity of SPS1 Arabidopsis thaliana
fibrillin 5B FBN5-B, fibrillin 5B specifically interacts with solanesyl diphosphate synthase 2, which biosynthesize the solanesyl moiety of plastoquinone-9. Plants containing defective FBN5-B accumulate less plastoquinone-9 and its cyclized product, plastochromanol-8, but the levels of tocopherols are not affected. Homozygous mutations in FBN5 are seedling-lethal. FBN5-B is required for PQ-9 biosynthesis through its interaction with enzyme SPS. FBN5 binding to the hydrophobic solanesyl moiety, which is generated by SPS2, in FBN5 B/SPS homodimeric complexes stimulates the enzyme activity of SPS2 Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast
-
 Arabidopsis thaliana 9507
-

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q76FS5 gene AtSPS2
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Arabidopsis thaliana Q8S948 gene AtSPS1
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Arabidopsis thaliana Col-0 Q76FS5 gene AtSPS2
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Arabidopsis thaliana Col-0 Q8S948 gene AtSPS1
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Synonyms

Synonyms Comment Organism
AtSPS1
-
 Arabidopsis thaliana
AtSPS2
-
 Arabidopsis thaliana
solanesyl diphosphate synthase
-
 Arabidopsis thaliana

General Information

General Information Comment Organism
metabolism FBN5-B is required for plastoquinone-9 biosynthesis through its interaction with enzyme SPS Arabidopsis thaliana
metabolism the enzyme is involved in the biosynthesis of solanesyl diphosphate and plastoquinone-9 Arabidopsis thaliana
metabolism the enzyme is involved in the biosynthesis of solanesyl diphosphate and plastoquinone-9. FBN5-B is required for plastoquinone-9 biosynthesis through its interaction with enzyme SPS Arabidopsis thaliana