Literature summary for 2.5.1.78 extracted from

Du, Z.; Li, X.; Wang, J.
Immunogenicity analysis of a novel subunit vaccine candidate molecule - recombinant L7/L12 ribosomal protein of Brucella suis (2016), Appl. Biochem. Biotechnol., 179, 1445-1455.

Search for more literature for 2.5.1.78

Application

Application	Comment	Organism
medicine	Brucella suis lumazine synthase (BLS) molecule is a favorable transport vector for antigenic protein, e.g. rL7/L12-BLS fusion protein, in vaccination, e.g. for antibody production in Oryctolagus cuniculus. The BLS molecule also has adjuvant property for improving immunity stimulation effects, when a foreign protein antigen is covalently attached to it	Brucella suis

Cloned(Commentary)

Cloned (Comment)	Organism
gene ribH2, recombinant coexpression of protein rL7/L12 with enzyme BLS as fusion protein in Escherichia coli strain BL21(DE3). The Bs-l7/l12 gene is cloned into a specific pET-28-a expression vector, which is inserted by the Brucella lumazine synthase enzyme gene, to form the pET-28-a-l7/l12-bls fusion gene expression vector	Brucella suis

Organism

Organism	UniProt	Comment	Textmining
Brucella suis	P61711	gene ribH2	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant Bs-l7/l12-BLS fusion protein from Escherichia coli strain BL21(DE3)	Brucella suis

Synonyms

Synonyms	Comment	Organism
BLS	-	Brucella suis
DMRL synthase 2	UniProt	Brucella suis
lumazine synthase	-	Brucella suis
lumazine synthase 2	UniProt	Brucella suis
type II lumazine synthase	UniProt	Brucella suis

General Information

General Information	Comment	Organism
physiological function	Brucella lumazine synthase (BLS) molecule is a favorable transport vector for antigenic protein	Brucella suis

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)