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Literature summary for 2.5.1.78 extracted from

  • Kumar, P.; Singh, M.; Karthikeyan, S.
    Crystal structure analysis of icosahedral lumazine synthase from Salmonella typhimurium, an antibacterial drug target (2011), Acta Crystallogr. Sect. D, 67, 131-139.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Salmonella enterica subsp. enterica serovar Typhimurium

Crystallization (Commentary)

Crystallization (Comment) Organism
at 3.57 A resolution. Crystals belong to monoclinic space group P21, with 60 subunits per asymmetric unit, packed as an icosahedron. Enzyme contains an N-terminal proline residue Salmonella enterica subsp. enterica serovar Typhimurium

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
16008
-
x * 16008, calculated, x * 17000-18000, SDS-PAGE, x * 18100, MALDI-TOF Salmonella enterica subsp. enterica serovar Typhimurium
18100
-
x * 16008, calculated, x * 17000-18000, SDS-PAGE, x * 18100, MALDI-TOF Salmonella enterica subsp. enterica serovar Typhimurium

Organism

Organism UniProt Comment Textmining
Salmonella enterica subsp. enterica serovar Typhimurium P66038
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-amino-6-ribitylamino-2,4-(1H,3H)-pyrimidinedione + 3,4-dihydroxy-2-butanone 4-phosphate
-
Salmonella enterica subsp. enterica serovar Typhimurium 6,7-dimethyl-8-ribityllumazine + 2 H2O + phosphate
-
?

Subunits

Subunits Comment Organism
? x * 16008, calculated, x * 17000-18000, SDS-PAGE, x * 18100, MALDI-TOF Salmonella enterica subsp. enterica serovar Typhimurium