Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.5.1.73 extracted from

  • Helgadottir, S.; Sinapah, S.; Soell, D.; Ling, J.
    Mutational analysis of Sep-tRNA:Cys-tRNA synthase reveals critical residues for tRNA-dependent cysteine formation (2012), FEBS Lett., 586, 60-63.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.5.1.73

Protein Variants

Protein Variants Comment Organism
C272S complete loss of activity Methanocaldococcus jannaschii
C64S complete loss of activity Methanocaldococcus jannaschii
C67S complete loss of activity Methanocaldococcus jannaschii
D182A 107% of wild-type activity Methanocaldococcus jannaschii
H126A complete loss of activity Methanocaldococcus jannaschii
H233A complete loss of activity Methanocaldococcus jannaschii
H325A 124% of wild-type activity Methanocaldococcus jannaschii
K234A complete loss of activity Methanocaldococcus jannaschii
K265A complete loss of activity Methanocaldococcus jannaschii
K354A/R356A 92% of wild-type activity Methanocaldococcus jannaschii
K370A 33% of wild-type activity Methanocaldococcus jannaschii
additional information active-site cysteine residues Cys39, Cys42 and Cys247 are essential for enzymic activity Methanocaldococcus jannaschii
N187A 85% of wild-type activity Methanocaldococcus jannaschii
N208A 101% of wild-type activity Methanocaldococcus jannaschii
R102A complete loss of activity Methanocaldococcus jannaschii
R292A 99% of wild-type activity Methanocaldococcus jannaschii
R96A 89% of wild-type activity Methanocaldococcus jannaschii
S231A complete loss of activity Methanocaldococcus jannaschii
Y127A 35% of wild-type activity Methanocaldococcus jannaschii

Organism

Organism UniProt Comment Textmining
Methanocaldococcus jannaschii Q59072
-
-

Synonyms

Synonyms Comment Organism
SepCysS
-
 Methanocaldococcus jannaschii