Literature summary for 2.5.1.7 extracted from

Klein, C.D.; Bachelier, A.
Molecular modeling and bioinformatical analysis of the antibacterial target enzyme MurA from a drug design perspective (2006), J. Comput. Aided Mol. Des., 20, 621-628.

Search for more literature for 2.5.1.7

Inhibitors

Inhibitors	Comment	Organism	Structure
fosfomycin	selectively inhibited by fosfomycin, which forms a covalent bond to the sulfhydryl group of the catalytically relevant Cys115 residue	Enterobacter cloacae
fosfomycin	selectively inhibited by fosfomycin, which forms a covalent bond to the sulfhydryl group of the catalytically relevant Cys115 residue	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Enterobacter cloacae	-	-	-
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine	-	Escherichia coli	phosphate + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine	-	?
phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine	-	Enterobacter cloacae	phosphate + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine	-	?

Synonyms

Synonyms	Comment	Organism
MurA	-	Escherichia coli
MurA	-	Enterobacter cloacae
UDP-N-acetylglucosamine enolpyruvyl transferase	-	Escherichia coli
UDP-N-acetylglucosamine enolpyruvyl transferase	-	Enterobacter cloacae

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Release 2023.1 (January 2023)