Literature summary for 2.5.1.63 extracted from

Li, X.G.; Domarkas, J.; OHagan, D.
Fluorinase mediated chemoenzymatic synthesis of [18F]-fluoroacetate (2010), Chem. Commun. (Camb. ), 46, 7819-7821.

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Application

Application	Comment	Organism
synthesis	preparation of sodium [18F]-fluoroacetate by generation of 5'-[18F]-fluoro-5'-deoxyadenosine by a fluorinase catalysed reaction of S-adenosyl-L-methionine with no carrier added [18F]-fluoride and then oxidation to [18F]-fluoroacetate by a Kuhn-Roth oxidative degradation. Na [18F]-fluoroacetate can be synthesized in 96% radiochemical purity	Streptomyces cattleya

Organism

Organism	UniProt	Comment	Textmining
Streptomyces cattleya	F8JPG4	-	-
Streptomyces cattleya ATCC 35852	F8JPG4	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + fluoride	-	Streptomyces cattleya	5'-deoxy-5'-fluoroadenosine + L-methionine	-	?
S-adenosyl-L-methionine + fluoride	-	Streptomyces cattleya ATCC 35852	5'-deoxy-5'-fluoroadenosine + L-methionine	-	?

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Release 2023.1 (January 2023)