Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.5.1.60 extracted from

  • Baron, R.A.; Seabra, M.C.
    Rab geranylgeranylation occurs preferentially via the pre-formed REP-RGGT complex and is regulated by geranylgeranyl pyrophosphate (2008), Biochem. J., 415, 67-75.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
Rab escort protein RGGT increases the ability of Rab escort protein to extract endogenous prenylated Rabs from membranes in vitro by stabilizing a soluble Rab escort protein-RGGT-geranylgeranylated Rab complex Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Sf9 cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
nickel-Sepharose affinity chromatography Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
geranylgeranyl diphosphate + protein-cysteine
-
Homo sapiens S-geranylgeranyl-protein + diphosphate
-
?

Synonyms

Synonyms Comment Organism
Rab geranylgeranyl transferase
-
Homo sapiens
RGGT
-
Homo sapiens