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Literature summary for 2.5.1.60 extracted from
- Protein prenyltransferases (2003), Genome Biol., 4, 212.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| geranylgeranyl diphosphate + protein-cysteine | Homo sapiens | the enzyme catalyzes posttranslational modification of proteins, the farnesyl moieties attached to the substrates are directly involved in protein-protein interactions as well as in protein-membrane interactions | S-geranylgeranyl-protein + diphosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| geranylgeranyl diphosphate + protein-cysteine | the enzyme catalyzes posttranslational modification of proteins, the farnesyl moieties attached to the substrates are directly involved in protein-protein interactions as well as in protein-membrane interactions | Homo sapiens | S-geranylgeranyl-protein + diphosphate | - |
? | |
| geranylgeranyl diphosphate + protein-cysteine | substrate motif: carboxy-terminal motifs such as -CC, -CXC, -CCX, -CCXX, -CCXXX, or CXXX | Homo sapiens | S-geranylgeranyl-protein + diphosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| geranylgeranyltransferase II | - |
Homo sapiens |
| GGT2 | - |
Homo sapiens |
| RabGGT | - |
Homo sapiens |
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