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Literature summary for 2.5.1.6 extracted from

  • Yang, H.; Ara, A.I.; Magilnick, N.; Xia, M.; Ramani, K.; Chen, H.; Lee, T.D.; Mato, J.M.; Lu, S.C.
    Expression pattern, regulation, and functions of methionine adenosyltransferase 2beta splicing variants in hepatoma cells (2008), Gastroenterology, 134, 281-291.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.5.1.6

Activating Compound

Activating Compound Comment Organism Structure
Tumor necrosis factor alpha induces expression of variant 1 (but not variant 2) MAT2beta Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Hep-G2 cells, HuH-7 cells, and HCC cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland mainly MAT2beta variant 1 Homo sapiens
-
brain mainly MAT2beta variant 1 Homo sapiens
-
heart mainly MAT2beta variant 2 Homo sapiens
-
hepatoma cell
-
 Homo sapiens
-
kidney MAT2beta variant 1 and 2 Homo sapiens
-
liver mainly MAT2beta variant 1 Homo sapiens
-
lung mainly MAT2beta variant 1 Homo sapiens
-
additional information almost no expression of MAT2beta variant 1 or 2 in bone marrow, trachea, salivary gland, uterus, adult liver, and placenta Homo sapiens
-
prostate gland mainly MAT2beta variant 1 Homo sapiens
-
skeletal muscle mainly MAT2beta variant 2 Homo sapiens
-
spinal cord mainly MAT2beta variant 1 Homo sapiens
-
testis mainly MAT2beta variant 2 Homo sapiens
-
thymus MAT2beta variant 1 and 2 Homo sapiens
-
thyroid gland mainly MAT2beta variant 1 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-methionine + H2O
-
 Homo sapiens phosphate + diphosphate + S-adenosyl-L-methionine
-
 ?

Synonyms

Synonyms Comment Organism
MAT2beta regulatory subunit Homo sapiens
methionine adenosyltransferase 2beta
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens