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Literature summary for 2.5.1.6 extracted from

  • Hu, X.; Chu, J.; Zhang, S.; Zhuang, Y.; Wang, Y.; Zhu, S.; Zhu, Z.; Yuan, Z.
    A novel feeding strategy during the production phase for enhancing the enzymatic synthesis of S-adenosyl-L-methionine by methylotrophic Pichia pastoris (2007), Enzyme Microb. Technol., 40, 669-674.
No PubMed abstract available

Activating Compound

Activating Compound Comment Organism Structure
additional information methanol induces enzyme expression and S-adenosyl-L-methionine production, while glycerol does not Komagataella pastoris

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Komagataella pastoris

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-methionine + H2O Komagataella pastoris
-
phosphate + diphosphate + S-adenosyl-L-methionine
-
?
ATP + L-methionine + H2O Komagataella pastoris GS115
-
phosphate + diphosphate + S-adenosyl-L-methionine
-
?

Organism

Organism UniProt Comment Textmining
Komagataella pastoris
-
-
-
Komagataella pastoris GS115
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information development of a feeding strategy during the production phase for enhancing the enzymatic synthesis of S-adenosyl-L-methionine, overview Komagataella pastoris
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-methionine + H2O
-
Komagataella pastoris phosphate + diphosphate + S-adenosyl-L-methionine
-
?
ATP + L-methionine + H2O
-
Komagataella pastoris GS115 phosphate + diphosphate + S-adenosyl-L-methionine
-
?

Synonyms

Synonyms Comment Organism
MAT
-
Komagataella pastoris

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Komagataella pastoris

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
assay at Komagataella pastoris

Cofactor

Cofactor Comment Organism Structure
ATP
-
Komagataella pastoris