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Literature summary for 2.5.1.6 extracted from

  • Chou, T.C.; Talalay, P.
    Inhibition of ATP: L-methionine S-adenosyltransferase of bakers yeast by structural analogues of ATP (1973), Biochim. Biophys. Acta, 321, 467-474.
    View publication on PubMed
Search for more literature for 2.5.1.6

Inhibitors

Inhibitors Comment Organism Structure
alpha,beta-methylene-adenosine tetraphosphate
-
 Saccharomyces cerevisiae
alpha,beta-methylene-ATP
-
 Saccharomyces cerevisiae
beta,gamma-methylene-ATP
-
 Saccharomyces cerevisiae
CTP
-
 Saccharomyces cerevisiae
dGTP
-
 Saccharomyces cerevisiae
diphosphate
-
 Saccharomyces cerevisiae
GDP
-
 Saccharomyces cerevisiae
GTP
-
 Saccharomyces cerevisiae
phosphate
-
 Saccharomyces cerevisiae
Tetrapolyphosphate
-
 Saccharomyces cerevisiae
tripolyphosphate
-
 Saccharomyces cerevisiae
TTP
-
 Saccharomyces cerevisiae
UTP
-
 Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2'-deoxy-ATP + L-methionine + H2O completely specific for ATP Saccharomyces cerevisiae ?
-
 ?
3'-deoxy-ATP + L-methionine + H2O completely specific for ATP Saccharomyces cerevisiae ?
-
 ?
ATP + L-methionine + H2O completely specific for ATP Saccharomyces cerevisiae S-adenosyl-L-methionine + phosphate + diphosphate
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
additional information
-
 additional information Ki values for several phosphonate analogues and nucleotides Saccharomyces cerevisiae
0.05
-
 tripolyphosphate
-
 Saccharomyces cerevisiae
0.18
-
 Tetrapolyphosphate
-
 Saccharomyces cerevisiae