Literature summary for 2.5.1.58 extracted from

Yang, S.H.; Chang, S.Y.; Andres, D.A.; Spielmann, H.P.; Young, S.G.; Fong, L.G.
Assessing the efficacy of protein farnesyltransferase inhibitors in mouse models of progeria (2010), J. Lipid Res., 51, 400-405.

Application

Application	Comment	Organism
medicine	possible target of therapy of Hutchinson-Gilford progeria syndrome by inhibiting protein farnesylation	Mus musculus

Inhibitors	Comment	Organism	Structure
ABT-100	-	Mus musculus

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Synonyms	Comment	Organism
farnesyltransferase	-	Mus musculus

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Release 2023.1 (January 2023)