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Literature summary for 2.5.1.58 extracted from
- Farnesyltransferase inhibitors and their potential role in therapy for myelodysplastic syndromes and acute myeloid leukaemia (2008), Br. J. Haematol., 141, 576-586.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| BMS-214662 | - |
Homo sapiens |  |
| L778123 | - |
Homo sapiens | |
| manumycin | - |
Homo sapiens | |
| R115777 | tipifarnib | Homo sapiens | |
| SCH66336 | lonafarnib | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| farnesyl diphosphate + Ras protein | - |
Homo sapiens | diphosphate + S-farnesyl Ras protein | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| FTase | - |
Homo sapiens |
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