Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2Z,6E)-3-(3-methylbut-2-enyl)-7,11-dimethyldodeca-2,6,10-triene monophosphate | IC50: 16 nM | Homo sapiens | |
(2Z,6E)-3-allyl-7,11-dimethyldodeca-2,6,10-trien-1-yl 5-nitrofurfuryl N-methyl-N-(4-chlorobutyl)phosphoramidate | - |
Homo sapiens | |
(2Z,6E)-3-allyl-7,11-dimethyldodeca-2,6,10-triene monophosphate | - |
Homo sapiens | |
(2Z,6E)-3-tert-butyl-7,11-dimethyldodeca-2,6,10-trien-1-yl 5-nitrofurfuryl N-methyl-N-(4-chlorobutyl)phosphoramidate | - |
Homo sapiens | |
(2Z,6E)-3-tert-butyl-7,11-dimethyldodeca-2,6,10-triene monophosphate | IC50: 13 nM | Homo sapiens | |
(2Z,6E,10E)-3-(3-methyl-1-but-2-enyl)-7,11-dimethyldodeca-2,6,10-trien-1-yl 5-nitrofurfuryl N-methyl-N-(4-chlorobutyl)phosphoramidate | - |
Homo sapiens | |
3-allylfarnesol | potent inhibitor | Homo sapiens | |
3-allylfarnesyl diphosphate | IC50: 189 nM | Homo sapiens | |
3-tert-butylfarnesyl diphosphate | IC50: 31 nM | Homo sapiens | |
R-115777 | - |
Homo sapiens | |
SCH66336 | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Schwann cell line | - |
Homo sapiens | - |
STS-26T cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
farnesyl diphosphate + protein-cysteine | - |
Homo sapiens | diphosphate + S-farnesyl protein | - |
? |
Synonyms | Comment | Organism |
---|---|---|
FTase | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000013 | - |
IC50: 13 nM | Homo sapiens | (2Z,6E)-3-tert-butyl-7,11-dimethyldodeca-2,6,10-triene monophosphate | |
0.000016 | - |
IC50: 16 nM | Homo sapiens | (2Z,6E)-3-(3-methylbut-2-enyl)-7,11-dimethyldodeca-2,6,10-triene monophosphate | |
0.000031 | - |
IC50: 31 nM | Homo sapiens | 3-tert-butylfarnesyl diphosphate | |
0.000189 | - |
IC50: 189 nM | Homo sapiens | 3-allylfarnesyl diphosphate |