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Literature summary for 2.5.1.58 extracted from
- Peptide specificity of protein prenyltransferases is determined mainly by reactivity rather than binding affinity (2005), Biochemistry, 44, 15314-15324.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21(DE3) FPT/pET23a cells | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| farnesyl diphosphate + protein-cysteine | - |
Rattus norvegicus | diphosphate + S-farnesyl protein | - |
? |  |
| TKCVIA + farnesyl diphosphate | - |
Rattus norvegicus | TK-(S-farnesyl)CVIA + diphosphate | - |
? | |
| TKCVIC + farnesyl diphosphate | - |
Rattus norvegicus | diphosphate + ? | - |
? | |
| TKCVID + farnesyl diphosphate | - |
Rattus norvegicus | TK-(S-farnesyl)CVID + diphosphate | - |
? | |
| TKCVIF + farnesyl diphosphate | - |
Rattus norvegicus | TK-(S-farnesyl)CVIF + diphosphate | - |
? | |
| TKCVII + farnesyl diphosphate | - |
Rattus norvegicus | TK-(S-farnesyl)CVII + diphosphate | - |
? | |
| TKCVIL + farnesyl diphosphate | - |
Rattus norvegicus | TK-(S-farnesyl)CVIL + diphosphate | - |
? | |
| TKCVIM + farnesyl diphosphate | - |
Rattus norvegicus | TK-(S-farnesyl)CVIM + diphosphate | - |
? | |
| TKCVIN + farnesyl diphosphate | - |
Rattus norvegicus | TK-(S-farnesyl)CVIN + diphosphate | - |
? | |
| TKCVIQ + farnesyl diphosphate | - |
Rattus norvegicus | TK-(S-farnesyl)CVIQ + diphosphate | - |
? | |
| TKCVIR + farnesyl diphosphate | - |
Rattus norvegicus | TK-(S-farnesyl)CVIR + diphosphate | - |
? | |
| TKCVIS + farnesyl diphosphate | - |
Rattus norvegicus | TK-(S-farnesyl)CVIS + diphosphate | - |
? | |
| TKCVIT + farnesyl diphosphate | - |
Rattus norvegicus | TK-(S-farnesyl)CVIT + diphosphate | - |
? | |
| TKCVIV + farnesyl diphosphate | - |
Rattus norvegicus | TK-(S-farnesyl)CVIV + diphosphate | - |
? | |
| TKCVIY + farnesyl diphosphate | - |
Rattus norvegicus | TK-(S-farnesyl)CVIY + diphosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| FTase | - |
Rattus norvegicus |
| protein prenyltransferase | - |
Rattus norvegicus |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0005 | - |
TKCVID | - |
Rattus norvegicus | |
| 0.001 | - |
TKCVII | - |
Rattus norvegicus | |
| 0.001 | - |
TKCVIL | - |
Rattus norvegicus | |
| 0.001 | - |
TKCVIR | - |
Rattus norvegicus | |
| 0.0017 | - |
TKCVIY | - |
Rattus norvegicus | |
| 0.0021 | - |
TKCVIV | - |
Rattus norvegicus | |
| 0.0082 | - |
TKCVIF | - |
Rattus norvegicus | |
| 0.013 | - |
TKCVIN | - |
Rattus norvegicus | |
| 0.017 | - |
TKCVIT | - |
Rattus norvegicus | |
| 0.041 | - |
TKCVIM | - |
Rattus norvegicus | |
| 0.046 | - |
TKCVIA | in 50 mM N2-hydroxyethylpiperazine-N-2-hydroxypropanesulfonic acid-NaOH, pH 7.8, 5 mM MgCl2, and 2 mM tris(2-carboxyethyl)phosphine hydrochloride | Rattus norvegicus | |
| 0.161 | - |
TKCVIQ | - |
Rattus norvegicus | |
| 0.21 | - |
TKCVIS | - |
Rattus norvegicus | |
| 0.31 | - |
TKCVIC | - |
Rattus norvegicus | |
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