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Literature summary for 2.5.1.57 extracted from

  • Hagemeier, C.; Vischer, P.; Buddecke, E.
    Studies on the biosynthesis of N-acetylneuraminic acid in cultured arterial wall cells (1986), Biochem. Soc. Trans., 14, 1173-1174.
No PubMed abstract available
Search for more literature for 2.5.1.57

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
N-acetyl-D-mannosamine 6-phosphate + phosphoenolpyruvate + H2O Sus scrofa N-acetylneuraminic acid biosynthesis N-acetyl-neuraminate 9-phosphate + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
 porcine
-

Source Tissue

Source Tissue Comment Organism Textmining
aorta
-
 Sus scrofa
-
endothelial cell
-
 Sus scrofa
-
smooth muscle
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0013
-
 smooth muscle cells Sus scrofa
0.0015
-
 endothelial cells Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-acetyl-D-mannosamine 6-phosphate + phosphoenolpyruvate + H2O
-
 Sus scrofa N-acetyl-neuraminate 9-phosphate + phosphate
-
 ?
N-acetyl-D-mannosamine 6-phosphate + phosphoenolpyruvate + H2O N-acetylneuraminic acid biosynthesis Sus scrofa N-acetyl-neuraminate 9-phosphate + phosphate
-
 ?